1. Commensal Fungi in Health and Disease
Jose J. Limon, Joseph H. Skalski, David M. Underhill 
Cell Host & Microbe 
Volume 22, Issue 2, Pages (August 2017)
DOI: /j.chom
Copyright © 2017 Elsevier Inc. Terms and Conditions

2. Figure 1
Alterations in Commensal Fungi May Affect the Host in Diverse Ways
Changing intestinal fungi either by adding (probiotic) or subtracting (antifungal drugs) organisms can alter the makeup of the bacterial microbiota (1). Fungi detected by the intestinal immune system can lead to inflammatory or tolerant immune responses and can direct immune cell trafficking (2). Phagocytes digesting fungi can release fungal-derived molecules into circulation that may have immunoregulatory effects (3). Finally, intestinal fungi release and consume metabolites that can lead to activation or suppression of immune responses (4).
Cell Host & Microbe  , DOI: ( /j.chom )
Copyright © 2017 Elsevier Inc. Terms and Conditions