1. After Eighty Study
Trial design: Elderly patients with non–ST-elevation acute coronary syndrome (NSTE-ACS) were randomized to invasive therapy (n = 229) vs. conservative therapy (n = 228).
Results
(p < )
Death, MI, stroke, or urgent revascularization: 41% of the invasive group vs. 61% of the conservative group (p < )
Death: 25% vs. 27% (p = 0.53), respectively, for invasive vs. conservative therapy
MI: 17% vs. 30% (p = ), respectively, for invasive vs. conservative therapy
Stroke: 3% vs. 6% (p = 0.26), respectively, for invasive vs. conservative therapy 61 % 41
Conclusions
Among elderly patients with NSTE-ACS, invasive therapy was beneficial at reducing adverse cardiovascular events compared with conservative therapy
Invasive therapy
Conservative therapy
Presented by Dr. Nicolai Tegn at ACC 2015