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Aortic dissection in a young man with Loeys–Dietz syndrome

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1 Aortic dissection in a young man with Loeys–Dietz syndrome
Vojtech Melenovsky, MD, PhD, Marek Adamira, MD, Dana Kautznerova, MD, Ludek Voska, MD, Jiri Weichet, MD, PhD, Bart Loeys, MD, PhD, Jan Pirk, MD, PhD  The Journal of Thoracic and Cardiovascular Surgery  Volume 135, Issue 5, Pages e1 (May 2008) DOI: /j.jtcvs Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions

2 Figure 1 A, Computed tomographic angiogram at the presentation demonstrated extensive dissection of the aortic root. B, Histologic analysis of the aortic tissue (Sirius red stain) showed cystic medionecrosis. The Journal of Thoracic and Cardiovascular Surgery  , e1DOI: ( /j.jtcvs ) Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions

3 Figure 2 Postoperative magnetic resonance angiogram demonstrated diffuse arterial ellongations and tortuosities (arrows), most apparent in carotid + vertebral (A) and basilar (B) territories. The Journal of Thoracic and Cardiovascular Surgery  , e1DOI: ( /j.jtcvs ) Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions

4 Family tree presenting affected (dark) and unaffected relatives of the proband (arrow). Asterisks denote genotyped individuals. The Journal of Thoracic and Cardiovascular Surgery  , e1DOI: ( /j.jtcvs ) Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions

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