1. Mitosis Cell Division

2. First, Let’s Review ….

3. Cell Reproduction Let’s Review –
All cells are derived from pre-existing cells
New cells are produced for growth and to replace damaged or old cells

4. Types of Cell Reproduction
Asexual Reproduction - a single cell divides to make 2 new identical cells
Eg. Mitosis
Sexual Reproduction - two cells (egg & sperm) that are NOT identical to the original cells unite to form a zygote Eg. Meiosis

5. How does DNA make more DNA?
DNA Replication
How does DNA make more DNA?

6. Two new, identical DNA strands
DNA Replication
DNA must be copied or replicated before cell division
Each new cell will then have an identical copy of the DNA
Original DNA strand
Two new, identical DNA strands

7. The Cell Cycle

8. Cells prepare for Division Cell Divides into Identical cells
Cell Cycle
DNA Copied
Cells prepare for Division
Cells Mature
Daughter Cells
Cell Divides into Identical cells

9. Two identical copies of DNA
Interphase
Cell carries on its normal activities
Makes more cytoplasm & organelles
DNA is copied (“replicated”)
All cell structures needed for division are made (e.g. centrioles)
Original DNA
Two identical copies of DNA

10. Mitosis

11. Mitosis has 4 Stages 1. Prophase 2. Metaphase 3. Anaphase 4. Telophase

12. Vocabulary Chromosomes – threads of genetic material Chromatids
– a copied chromosome
Centromere
– “belt” that holds chromatids together
Spindle fiber
– “string” that attaches to chromosome
Centrioles
– produces the spindle fiber
Nuclear membrane
– envelope around the nucleus

13. Chromosomes in Dividing Cells
Duplicated chromosomes are called chromatids & are held together by the centromere
Called Sister Chromatids

14. Prophase

15. Prophase Spindle fibers forms from centrioles
Nuclear membrane is broken down
Spindle fibers attach to the centromere of each chromosome

16. Spindle Fiber attached to Chromosome

17. Metaphase

18. Metaphase Chromosomes move to the center of the cell
Chromosomes are now lined up at the equator (Middle = Metaphse)
Equator of Cell
Pole of the Cell

19. Metaphase
Spindle Fibers
Chromosomes lined at the Equator

20. Chromosomes at Equator
Metaphase
Chromosomes at Equator

21. Anaphase

22. Anaphase
Sister chromatids are pulled apart to opposite poles of the cell by spindle fibers

23. Sister Chromatids being separated
Anaphase
Sister Chromatids being separated

24. Telophase

25. Telophase Sister chromatids at opposite poles Spindle disassembles
Nuclear envelope forms around each set of sister chromatids
CYTOKINESIS occurs

26. Cytokinesis Means division of the cytoplasm
Division of cell into two, identical halves called daughter cells

27. Cleavage furrow in animal cell Cell plate in plant cell
Cytokinesis
Cleavage furrow in animal cell
Cell plate in plant cell

28. Daughter Cells of Mitosis
Have the same number of chromosomes as each other and as the parent cell from which they were formed

29. Identical Daughter Cells
Chromosome number the same, but cells smaller than parent cell

30. Review of Mitosis

31. P.M.A.T Key Words
Prophase – Plug together
Metaphase – Middle
Anaphase – Away
Telophase - Terminated

32. Name the Mitotic Stages:
Interphase
Name this?
Prophase
Telophase
Name this?
Metaphase
Anaphase

33. Name each stage as you see it occur?
Mitosis Animation
Name each stage as you see it occur?

34. Chromosomes during Metaphase of mitosis
Cell Division
Chromosomes during Metaphase of mitosis
Cytokinesis
Anaphase
Prophase
Metaphase
Telophase

35. Telophase & Cytokinesis
Identify the Stages ?
Prophase ? ? ?
Metaphase
Anaphase
Prophase ? ? ?
Telophase & Cytokinesis
Anaphase
Telophase

36. Locate the Four Mitotic Stages in Plants
Anaphase
Telophase
Metaphase
Prophase