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Volume 80, Issue 11, Pages 1222-1230 (December 2011)
Acute-on-chronic kidney injury at hospital discharge is associated with long-term dialysis and mortality Vin-Cent Wu, Tao-Min Huang, Chun-Fu Lai, Chih-Chung Shiao, Yu-Feng Lin, Tzong-Shinn Chu, Pei-Chen Wu, Chia-Ter Chao, Jann- Yuan Wang, Tze-Wah Kao, Guang-Huar Young, Pi-Ru Tsai, Hung-Bin Tsai, Chieh-Li Wang, Ming-Shou Wu, Wen-Chih Chiang, I-Jung Tsai, Fu-Chang Hu, Shuei-Liong Lin, Yung-Ming Chen, Tun-Jun Tsai, Wen-Je Ko, Kwan-Dun Wu Kidney International Volume 80, Issue 11, Pages (December 2011) DOI: /ki Copyright © 2011 International Society of Nephrology Terms and Conditions
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Figure 1 Flow diagram of the study population. AKI, acute kidney injury; CKD, chronic kidney disease; ESRD, end-stage renal disease; ICU, intensive care unit; RIFLE, risk, injury, failure, loss, and end stage. Kidney International , DOI: ( /ki ) Copyright © 2011 International Society of Nephrology Terms and Conditions
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Figure 2 Long-term survival stratified by CKD and AKI. Cox proportional hazard model for long-term survival of patients alive at hospital discharge, stratified by severity of AKI for non-CKD patients and by occurrence of AKI for CKD patients (non-CKD patients were categorized into non-AKI, risk, injury, and failure groups; CKD patients were categorized into non-AKI and AKI groups, all P<0.001, non-CKD–non-AKI was the reference). AKI, acute kidney injury; CKD, chronic kidney disease; CKD–AKI, acute-on-chronic kidney disease; ESRD, end-stage renal disease. Kidney International , DOI: ( /ki ) Copyright © 2011 International Society of Nephrology Terms and Conditions
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Figure 3 Long-term survival stratified by kidney recovery. Cox proportional hazard model for long-term survival of patients alive at hospital discharge, stratified by the status of kidney recovery. AKI, acute kidney injury; CKD, chronic kidney disease; ESRD, end-stage renal disease; R, recovery; non-R, non-recovery; Non-CKD–non-AKI was the reference; all P<0.001. Kidney International , DOI: ( /ki ) Copyright © 2011 International Society of Nephrology Terms and Conditions
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Figure 4 Long-term dialysis dependence stratified by CKD and AKI. Proportion of freedom from dialysis dependence of patients alive at hospital discharge, stratified by severity of AKI for non-CKD patients and by occurrence of AKI for CKD patients. AKI, acute kidney injury; CKD, chronic kidney disease; CKD–AKI, acute-on-chronic kidney disease; risk, P=0.056; injury, P=0.017; all others P< Non-CKD–non-AKI was the reference. Kidney International , DOI: ( /ki ) Copyright © 2011 International Society of Nephrology Terms and Conditions
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Figure 5 Long-term dialysis dependence stratified by kidney recovery. Proportion of freedom from dialysis dependence of patients alive at hospital discharge, stratified by the status of kidney recovery. AKI, acute kidney injury; CKD, chronic kidney disease; non-R, non-recovery; R, recovery; all P< Non-CKD–non-AKI was the reference. Kidney International , DOI: ( /ki ) Copyright © 2011 International Society of Nephrology Terms and Conditions
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