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Effects of pH Management During Selective Antegrade Cerebral Perfusion on Cerebral Microcirculation and Metabolism: Alpha-Stat Versus pH-Stat  Sebastian.

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Presentation on theme: "Effects of pH Management During Selective Antegrade Cerebral Perfusion on Cerebral Microcirculation and Metabolism: Alpha-Stat Versus pH-Stat  Sebastian."— Presentation transcript:

1 Effects of pH Management During Selective Antegrade Cerebral Perfusion on Cerebral Microcirculation and Metabolism: Alpha-Stat Versus pH-Stat  Sebastian Dahlbacka, MD, Hanna Alaoja, MS, Jussi Mäkelä, MS, Eija Niemelä, MS, Päivi Laurila, MD, PhD, Kai Kiviluoma, MD, PhD, Anna Honkanen, MS, Pasi Ohtonen, MS, Vesa Anttila, MD, PhD, Tatu Juvonen, MD, PhD  The Annals of Thoracic Surgery  Volume 84, Issue 3, Pages (September 2007) DOI: /j.athoracsur Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 Brain arterial diameters (left), adherent leukocytes (center), and tissue oxygenation (right) in pigs undergoing selective cerebral perfusion (SCP) and being monitored using either α-stat (solid squares; n = 10) or pH-stat (open circles; n = 10) strategy. (m = minutes; NADH = reduced nicotinamide adenine dinucleotide.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 Key brain microdialysis findings for brain lactate concentration (left), brain lactate to pyruvate ratio (center), and brain glycerol concentration (right) in pigs undergoing selective cerebral perfusion (SCP) and being monitored with either α-stat (solid squares; n = 12) or pH-stat (open circles; n = 12) strategy. (postop = postoperative.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions


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