1. Excitatory amino acid glutamate: role in peripheral nociceptive transduction and inflammation in experimental and clinical osteoarthritis 
Z.-H. Wen, Y.-C. Chang, Y.-H. Jean 
Osteoarthritis and Cartilage 
Volume 23, Issue 11, Pages (November 2015)
DOI: /j.joca
Copyright © 2015 Osteoarthritis Research Society International Terms and Conditions

2. Fig. 1
Working model of the expression and function of glutamatergic signaling mechanisms in the knee joint. Glutamate receptors are essential for signal input, glutamate transporters are essential for signal termination, and VGLUTs are essential for signal output through the condensation of glutamate into vesicular constituents for subsequent exocytotic release. Glutamate is converted into glutamine by the enzyme glutamine synthase.
Osteoarthritis and Cartilage  , DOI: ( /j.joca )
Copyright © 2015 Osteoarthritis Research Society International Terms and Conditions