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Neuroblastoma and Ewing's Sarcoma Associated with ROR1 Expression Can Be Effectively Targeted with NK Cells Modified to Express an Anti ROR1 Chimeric.

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Presentation on theme: "Neuroblastoma and Ewing's Sarcoma Associated with ROR1 Expression Can Be Effectively Targeted with NK Cells Modified to Express an Anti ROR1 Chimeric."— Presentation transcript:

1 Neuroblastoma and Ewing's Sarcoma Associated with ROR1 Expression Can Be Effectively Targeted with NK Cells Modified to Express an Anti ROR1 Chimeric Antigen Receptor  Mona Elmacken, MD, Aradhana Awasthi, PhD, Janet Ayello, MS, MT(ASCP), Carmella van de Ven, MS, Wen Luo, PhD, Yanling Liao, PhD, Stanley Riddell, MD, Mitchell S. Cairo, MD  Biology of Blood and Marrow Transplantation  Volume 21, Issue 2, Pages S95-S97 (February 2015) DOI: /j.bbmt Copyright © Terms and Conditions

2 Figure 1 Anti-R0R1 expression in transfected NK cells.
Biology of Blood and Marrow Transplantation  , S95-S97DOI: ( /j.bbmt ) Copyright © Terms and Conditions

3 Figure 2 Anti-R0R1-CAR-NK cytotoxicity at 48 hours.
Biology of Blood and Marrow Transplantation  , S95-S97DOI: ( /j.bbmt ) Copyright © Terms and Conditions


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