1. Nat. Rev. Rheumatol. doi:10.1038/nrrheum.2016.131
Figure 2 Expression of inhibitory immune receptors on different immune cells
Figure 2 | Expression of inhibitory immune receptors on different immune cells. Various inhibitory receptors are expressed by T cells (part a), B cells (part b), dendritic cells (DCs) and macrophages (part c) and neutrophils (part d). The figure shows the ligands for inhibitory receptors discussed in this Review and, where relevant, shows the co-stimulatory receptors that share these ligands. BDCA2, blood-derived dendritic cell antigen 2; CD200R1, CD200 receptor 1; CTLA4, cytotoxic T-lymphocyte-associated antigen 4; FcγRIIB, low-affinity immunoglobulin-γ Fc region receptor IIb; PECAM1, platelet endothelial cell adhesion molecule; PILRα, paired immunoglobulin-like type 2 receptor-α; PD1, programmed cell death protein 1; PDL1, PD1 ligand 1; PVR, poliovirus receptor; TIGIT, T-cell immunoreceptor with immunoglobulin and ITIM domains; VISTA, V-type immunoglobulin domain suppressor of T cell activation; VISTA-R, VISTA receptor (unknown); VSTM1, V-set and transmembrane domain-containing protein 1; VSTM1-L, VSTM1 ligand (unknown).
van der Vlist, M. et al. (2016) Immune checkpoints and rheumatic diseases: what can cancer immunotherapy teach us?
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