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CMV in the HSCT Recipient

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Presentation on theme: "CMV in the HSCT Recipient"— Presentation transcript:

1 CMV in the HSCT Recipient

2

3 Allogenic Stem Cell Transplantation Where Are We?

4 CMV Infections After HSCT

5 Concerns for Increased Risk of CMV Infection

6 Burden of Disease Mortality and Cost

7 Approaches to CMV Preemptive Therapy

8 Approaches to CMV Testing

9 CMV VL Testing Challenges

10 Considerations When Monitoring CMV VL

11 Preemptive Strategies DNA CMV Polymerase Inhibitors

12 Concerns With Prophylaxis

13 Where Have We Made Progress?

14 Maribavir: Treatment Phase 2: Initially Promising

15 Maribavir: Prophylaxis Phase 3: No Difference When Compared With PBO

16 Brincidofovir for CMV Prevention Phase 2

17 Brincidofovir for CMV Prevention Phase 3

18 Letermovir for CMV Prevention Phase 3

19 Letermovir Safety Results

20 Impacts on Practice Use of Letermovir

21 Impacts on Practice Drug-Drug Concerns

22 Moving Forward

23 Concluding Remarks

24 Abbreviations

25 Abbreviations (cont)


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