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Increased expression of p21-activated kinase in adenomyosis
So Ra Kim, M.D., M.S., Sung Hoon Kim, M.D., Ph.D., Hoi Woul Lee, M.S., Hee Dong Chae, M.D., Ph.D., Chung-Hoon Kim, M.D., Ph.D., Byung Moon Kang, M.D., Ph.D. Fertility and Sterility Volume 94, Issue 3, Pages (August 2010) DOI: /j.fertnstert Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions
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Figure 1 (A) Representative micrographs (×100; inset ×400) of Pak1 immunostaining in the normal endometrium (a, d, g, j), eutopic endometrium of women with adenomyosis (b, e, h, k), and adenomyosis foci (c, f, i, l). a: normal endometrium in the early proliferative phase, b: eutopic endometrium of women with adenomyosis in the early proliferative phase, c: adenomyosis foci in the early proliferative phase, d: normal endometrium in the early secretory phase, e: eutopic endometrium of women with adenomyosis in the early secretory phase, f: adenomyosis foci in the early secretory phase, g: normal endometrium in the midsecretory phase, h: eutopic endometrium of women with adenomyosis in the midsecretory phase, i: adenomyosis foci in the midsecretory phase, j: normal endometrium in the late secretory phase, k: eutopic endometrium of women with adenomyosis in the late secretory phase, l: adenomyosis foci in the late secretory phase. (B) HSCORES of Pak1 immunostaining in endometrial stromal cells throughout the menstrual cycle. (C) HSCORES of Pak1 immunostaining in endometrial glandular cells throughout the menstrual cycle. W: whole menstrual stages put together, P: proliferative phase, S: secretory phase, ES: early secretory phase, MS: midsecretory phase, LS: late secretory phase. Each number in the bars indicates the number of samples recruited. Data of HSCORES are expressed as mean ± SEM. †††P<.001, ††P<.01, †P<.05 versus the controls as well as the eutopic endometrium of women with adenomyosis, respectively; ∗∗∗P<.001, ∗∗P<.01, ∗P<.05 versus the controls, respectively. Fertility and Sterility , DOI: ( /j.fertnstert ) Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions
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