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Activity-Based Profiling of 2-Oxoglutarate Oxygenases

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Presentation on theme: "Activity-Based Profiling of 2-Oxoglutarate Oxygenases"— Presentation transcript:

1 Activity-Based Profiling of 2-Oxoglutarate Oxygenases
Paul P. Geurink, Bogdan I. Florea, Herman S. Overkleeft  Chemistry & Biology  Volume 18, Issue 5, Pages (May 2011) DOI: /j.chembiol Copyright © 2011 Elsevier Ltd Terms and Conditions

2 Figure 1 Rational Design of Activity-Based 2-OG Probes
(A) General mechanism of 2-oxoglutarate-dependent oxygenases. (B) Activity-based 2-OG probes employed in the highlighted studies. (C) General flowscheme of activity-based 2-OG profiling. Chemistry & Biology  , DOI: ( /j.chembiol ) Copyright © 2011 Elsevier Ltd Terms and Conditions

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