1. The network www.hic-vac.org Name email Date

2. What is HIC-Vac? ~£3m, 4 year MRC & BBSRC-funded network
Support, develop and advocate the use of volunteer controlled infection studies, in order to:
Improve understanding of infections and the diseases they cause
Enhance the development of new/better vaccines & treatments

3. Experimental Human Infection Models “are on the rise”
The UK has unique strengths
Extensive infrastructure
Need and utility is great: new vaccines, rapid advances in immunological understanding
Strong commercial buy-in
All our investigators work on LMIC diseases and/or have LMIC collaborators
Experimental Human Infection Models “are on the rise”

4. Volunteers are willing to do a lot…

5. Our shared objectives UNDERPINNING
Facilitate and support regulatory and ethical structures
Enhance and support applications to science funders
Enhance public understanding of HIC in the UK/LMICs
Enable and de-risk phase III vaccine studies
NETWORKING
Create an interactive, supportive network of investigators
Form bridges between the UK and LMICs
Exchange of eligible volunteers between programmes

6. Network Management Board
Name
Surname
Institution
Peter
Openshaw
Imperial College London (Director)
Andrew
Pollard
University of Oxford (Deputy Director)
Stephen
Gordon
Liverpool School of Tropical Medicine &
Malawi-Liverpool-Wellcome Trust Clinical Research Programme
Cherry
Kang
Translational Health Science and Technology Institute, India
Daniela
Ferreira
Liverpool School of Tropical Medicine
Robert
Read
University of Southampton
Meta
Roestenberg
Leiden University Medical Center
John
Tregoning
Imperial College London

7. Membership Total members June, 2018: 134
Investigators (59): Independent current HIC studies
Associates (50): Work with Investigators (Postdoc etc.)
Affiliates (25): Others interested in HIC studies
What we provide:
Eligibility to apply for HIC-Vac funding
Invitations to meetings and events
Profile on website – networking and collaborations
HIC-Vac mailing list for network notices

8. UK Members

9. Worldwide Members
134 members across 23 different countries

10. Pathogens we’d like new or better vaccines against…

11. Events
All our events are listed on our website: November 2017 Kick off meeting, Oxford 6 February 2018 Academy of Medical Sciences Regulatory Workshop, London June 2018 Sandpit event with knowinnovation, Oxford November 2018 HIC-Vac Annual Meeting, Liverpool November 2019 HIC-Vac Annual Meeting, LMIC location

12. www.hic-vac.org @hic_vac