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A Dual Binding Receptor for ER-phagy

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Presentation on theme: "A Dual Binding Receptor for ER-phagy"— Presentation transcript:

1 A Dual Binding Receptor for ER-phagy
Noboru Mizushima  Developmental Cell  Volume 44, Issue 2, Pages (January 2018) DOI: /j.devcel Copyright © 2018 Elsevier Inc. Terms and Conditions

2 Figure 1 ER-phagy Receptors
ER-phagy receptors that have been identified are shown. Saccharomyces cerevisiae have Atg39 and Atg40, whereas mammals have FAM134B, SEC62, RTN3, and CCPG1. All of these contain at least one LC3-interacting region (LIR) or Atg8-interacting motif (AIM). Additionally, CCPG1 has two FIP200-interacting regions (FIRs), and Atg39 has one Atg11-binding region (11BR). The Atg11-binding region in Atg40 is not yet identified. TM, transmembrane domain; RHD, reticulon-homology domain. Figure created by Haruka Chino. Developmental Cell  , DOI: ( /j.devcel ) Copyright © 2018 Elsevier Inc. Terms and Conditions

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