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Nagashima-Type Palmoplantar Keratosis: A Common Asian Type Caused by SERPINB7 Protease Inhibitor Deficiency  Akiharu Kubo  Journal of Investigative Dermatology 

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1 Nagashima-Type Palmoplantar Keratosis: A Common Asian Type Caused by SERPINB7 Protease Inhibitor Deficiency  Akiharu Kubo  Journal of Investigative Dermatology  Volume 134, Issue 8, Pages (August 2014) DOI: /jid Copyright © 2014 The Society for Investigative Dermatology, Inc Terms and Conditions

2 Figure 1 Clinical appearance of Nagashima-type palmoplantar keratosis. (a, b) “Transgrediens” of the reddish mild hyperkeratosis on the dorsal surfaces of the feet and Achilles tendon area. (c, d) Whitish spongy changes on the hands after 10 minutes of water exposure. (d) “Transgrediens” on the dorsal surfaces of the hands. Journal of Investigative Dermatology  , DOI: ( /jid ) Copyright © 2014 The Society for Investigative Dermatology, Inc Terms and Conditions


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