1. Volume 131, Issue 3, Pages 704-712 (September 2006)
Endoscopic Full-Thickness Plication for the Treatment of Gastroesophageal Reflux Disease: A Randomized, Sham-Controlled Trial 
Richard Rothstein, Charles Filipi, Karel Caca, Ronald Pruitt, Klaus Mergener, Alfonso Torquati, Gregory Haber, Yang Chen, Kenneth Chang, David Wong, Jacques Deviere, Douglas Pleskow, Charles Lightdale, Alain Ades, Richard Kozarek, William Richards, Anthony Lembo 
Gastroenterology 
Volume 131, Issue 3, Pages (September 2006)
DOI: /j.gastro
Copyright © 2006 American Gastroenterological Association (AGA) Institute Terms and Conditions

2. Figure 1
Study design.
Gastroenterology  , DOI: ( /j.gastro )
Copyright © 2006 American Gastroenterological Association (AGA) Institute Terms and Conditions

3. Figure 2 The Plicator system.
Gastroenterology  , DOI: ( /j.gastro )
Copyright © 2006 American Gastroenterological Association (AGA) Institute Terms and Conditions

4. Figure 3
The Plicator procedure. (A) Plicator retroflexed to gastroesophageal junction; tissue retractor advanced into gastric cardia. (B) Tissue withdrawn between Plicator arms. (C) Arms closed, transmural suture deployed. (D) Resulting full-thickness plication.
Gastroenterology  , DOI: ( /j.gastro )
Copyright © 2006 American Gastroenterological Association (AGA) Institute Terms and Conditions

5. Figure 4 Disposition of patients.
Gastroenterology  , DOI: ( /j.gastro )
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6. Figure 5
GERD-HRQL score ≥50% improvement at 3 months ( ) off medications (intention to treat). aP value from Fisher exact test.
Gastroenterology  , DOI: ( /j.gastro )
Copyright © 2006 American Gastroenterological Association (AGA) Institute Terms and Conditions

7. Figure 6
GERD-HRQL scores (intention to treat). aP value from a paired t test. bP values for treatment comparisons are from an analysis of variance.
Gastroenterology  , DOI: ( /j.gastro )
Copyright © 2006 American Gastroenterological Association (AGA) Institute Terms and Conditions

8. Figure 7
PPI use (intention to treat). aP values for treatment comparison are from Fisher exact test.
Gastroenterology  , DOI: ( /j.gastro )
Copyright © 2006 American Gastroenterological Association (AGA) Institute Terms and Conditions

9. Figure 8
Distal esophageal acid exposure. aP value from Wilcoxon signed rank test. bP value for treatment comparison from Wilcoxon rank sum test.
Gastroenterology  , DOI: ( /j.gastro )
Copyright © 2006 American Gastroenterological Association (AGA) Institute Terms and Conditions