1. Volume 25, Issue 1, Pages 63-69 (March 2018)
Protective effects of Artemisia campestris extract against gastric acid reflux-induced esophageal mucosa injuries 
Mohamed-Amine Jabri, Haifa Tounsi, Afifa Abdellaoui, Lamjed Marzouki, Hichem Sebai 
Pathophysiology 
Volume 25, Issue 1, Pages (March 2018)
DOI: /j.pathophys
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2. Pathophysiology 2018 25, 63-69DOI: (10.1016/j.pathophys.2018.01.001)
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3. Fig. 1
Phenolic compounds found in Artemisia campestris aqueous extract (ACAE).
Pathophysiology  , 63-69DOI: ( /j.pathophys )
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4. Fig. 2
Esophageal histology showing the protective effects of Artemisia campestris aqueous extract (ACAE) and (FAM) famotidine, and gallic acid (GA) on GER-induced esophageal. Animals were treated with vehicle (H2O), various doses of ACAE (100, 200 and 400 mg/kg, b.w., p.o.) or FAM (20 mg/kg, b.w., p.o.) during 6 h after esophagitis induction. (A) Control; (B) GER; (C, D and E) GER + ACAE (100, 200 and 400 mg/kg, b.w., p.o.) respectively and (F) GER + FAM (20 mg/kg, b.w., p.o.).
Pathophysiology  , 63-69DOI: ( /j.pathophys )
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5. Fig. 3
Effect of ACAE and famotidine (FAM) on GER-induced esophageal lipoperoxydation. Animals were treated with vehicle (H2O), various doses of ACAE (100, 200 and 400 mg/kg, b.w., p.o.) or FAM (20 mg/kg, b.w., p.o.) during 6 h after esophagitis induction. The data are expressed as mean ± SEM (n = 10). a: p < 0.05 compared to the control group, b: p < 0.05 compared to the esophagitis group c: p < 0.05 compared to ACAE-100 group and d: p < 0.05 compared to ACAE-200 (ANOVA test).
Pathophysiology  , 63-69DOI: ( /j.pathophys )
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6. Fig. 4
Effect of ACAE and famotidine (FAM) on GER-induced disturbance in esophageal thiol groups level. Animals were treated with vehicle (H2O), various doses of ACAE (100, 200 and 400 mg/kg, b.w., p.o.) or FAM (20 mg/kg, b.w., p.o.) during 6 h after esophagitis induction. The data are expressed as mean ± SEM (n = 10). a: p < 0.05 compared to the control group, b: p < 0.05 compared to the esophagitis group c: p < 0.05 compared to ACAE-100 group and d: p < 0.05 compared to ACAE-200 (ANOVA test).
Pathophysiology  , 63-69DOI: ( /j.pathophys )
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7. Fig. 5
Effect of ACAE and famotidine (FAM) on GER-induced disturbance in esophageal antioxidant enzyme activities: (A) superoxide dismutase (SOD), (B) catalase (CAT), and (C) glutathione peroxidase (GPx). Animals were treated with vehicle (H2O), various doses of ACAE (100, 200 and 400 mg/kg, b.w., p.o.) or FAM (20 mg/kg, b.w., p.o.) during 6 h after esophagitis induction. The data are expressed as mean ± SEM (n = 10). a: p < 0.05 compared to the control group, b: p < 0.05 compared to the esophagitis group c: p < 0.05 compared to ACAE-100 group and d: p < 0.05 compared to ACAE-200 (ANOVA test).
Pathophysiology  , 63-69DOI: ( /j.pathophys )
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