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Transplantation of Ex Vivo Expanded Umbilical Cord Blood (NiCord) Decreases Early Infection and Hospitalization  Sarah Anand, Samantha Thomas, Terry Hyslop,

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Presentation on theme: "Transplantation of Ex Vivo Expanded Umbilical Cord Blood (NiCord) Decreases Early Infection and Hospitalization  Sarah Anand, Samantha Thomas, Terry Hyslop,"— Presentation transcript:

1 Transplantation of Ex Vivo Expanded Umbilical Cord Blood (NiCord) Decreases Early Infection and Hospitalization  Sarah Anand, Samantha Thomas, Terry Hyslop, Janet Adcock, Kelly Corbet, Cristina Gasparetto, Richard Lopez, Gwynn D. Long, Ashley K. Morris, David A. Rizzieri, Keith M. Sullivan, Anthony D. Sung, Stefanie Sarantopoulos, Nelson J. Chao, Mitchell E. Horwitz  Biology of Blood and Marrow Transplantation  Volume 23, Issue 7, Pages (July 2017) DOI: /j.bbmt Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions

2 Figure 1 Cumulative incidence of time to ANC engraftment by study group (n = 104). Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions

3 Figure 2 Infection density for total (A), bacterial (B), and viral (C) infections in the NiCord (black) and standard UCB (gray) groups by infection grade. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions

4 Figure 3 Adjusted RRs (95% CI) for infection in the NiCord and standard UCB groups. Estimates are adjusted for age at transplantation, disease status, and acute grade II-IV GVHD by Poisson regression analysis (n = 104). Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions

5 Figure 4 Days alive and out of the hospital in the first 100 days by study group (unadjusted mean; 95% CI). Each data point represents the number of days spent out of the hospital by an individual patient in the first 100 days. A value of 0 indicates hospitalization during the entire 100 days or death during the initial hospital stay. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions


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