1. Relevance of H1-receptor occupancy to H1-antihistamine dosing in children 
Keith J. Simons, PhD, Margherita Strolin Benedetti, PhD, F. Estelle R. Simons, MD, FRCPC, Michel Gillard, PhD, Eugene Baltes, PhD 
Journal of Allergy and Clinical Immunology 
Volume 119, Issue 6, Pages (June 2007)
DOI: /j.jaci
Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2. Fig 1
A, Suppression of histamine-induced wheal versus levocetirizine unbound (free) plasma concentrations. B, Suppression of histamine-induced wheal versus levocetirizine H1-receptor occupancy.
Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci )
Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

3. Fig 2
A, Suppression of histamine-induced flare versus levocetirizine unbound (free) plasma concentrations. B, Suppression of histamine-induced flare versus levocetirizine H1-receptor occupancy.
Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci )
Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions