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Cell Fusion: An EFFicient Sculptor

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Presentation on theme: "Cell Fusion: An EFFicient Sculptor"— Presentation transcript:

1 Cell Fusion: An EFFicient Sculptor
Eric Witze, Joel H. Rothman  Current Biology  Volume 12, Issue 13, Pages R467-R469 (July 2002) DOI: /S (02)00948-X

2 Figure 1 Membrane fusion mechanisms.
(A) The coiled-coil domains of SNAREs bring vesicle and target membranes within close proximity, facilitating fusion. (B) In epidermal cell fusion in C. elegans, the apical junctions (AJ) hold the epidermal cells together where cell fusion is initiated. (C) A fusion pore forms at the apical junction of the membrane barrier and spreads outward behind the migrating junction. The two nuclei of the adjacent cells (N1, N2) share a common cytoplasm after fusion. Current Biology  , R467-R469DOI: ( /S (02)00948-X)


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