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Treatment with grass allergen peptides improves symptoms of grass pollen–induced allergic rhinoconjunctivitis  Anne K. Ellis, MD, MSc, FRCPC, Charles.

Published byАднан Милинковић Modified over 5 years ago

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Presentation on theme: "Treatment with grass allergen peptides improves symptoms of grass pollen–induced allergic rhinoconjunctivitis  Anne K. Ellis, MD, MSc, FRCPC, Charles."— Presentation transcript:

1 Treatment with grass allergen peptides improves symptoms of grass pollen–induced allergic rhinoconjunctivitis  Anne K. Ellis, MD, MSc, FRCPC, Charles W. Frankish, MD, FRCPC, Robyn E. O'Hehir, FRACP, PhD, Kristen Armstrong, MSc, PMP, Lisa Steacy, BSc, Mark Larché, PhD, Roderick P. Hafner, PhD  Journal of Allergy and Clinical Immunology  Volume 140, Issue 2, Pages (August 2017) DOI: /j.jaci Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2 Fig 1 Overall study design.
Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

3 Fig 2 Subject disposition. *Had TRSS of 8 or greater. †Had TRSS of less than 8. aOne subject withdrew because of an AE, 1 subject withdrew consent, and 1 subject was lost to follow-up. bTwo subjects withdrew because of AEs, 1 subject was lost to follow-up, 2 subjects were withdrawn because of protocol deviations, and 1 subject withdrew because of relocation. cOne subject withdrew because of an AE, 1 subject withdrew because of pregnancy, 1 subject was withdrawn because of a protocol deviation, and 1 subject withdrew because of a schedule conflict. dTwo subjects withdrew because of AEs, and 1 subject withdrew consent. Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

4 Fig 3 A and B, Improvement in TRSS in the mITT. n = 63 at the PTC visit on day 4. Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

5 Fig 4 A and B, Improvement in TRSSs in subjects with TRSSs of 12 or greater. n = 46 at the PTC visit on day 4. Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

6 Fig E1 Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

7 Fig E2 Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

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