1. Hematology & Immunology A & P 5
By Angie Lawson RN, BSN

2. Blood Plasma Albumin Serum Liquid portion of the blood
protein of highest concentration in the blood
Serum
Clear fluid portion of the blood

3. Blood Cells (Corpuscles)
RBC’s
Platelets -
WBC’s
Sticky,irregularly shaped, colorless blood cells

4. Origin of Blood Cells Hematopoiesis Stem Cell
the formation and development of the cells of the blood.
Stem Cell
undifferentiated cells which retain the ability to differentiate into other cell types

6. Depressed Bone Marrow Myelosuppression
The bone marrow makes fewer of all blood cells

7. Myelosuppression causes:
Anemia
aren't enough healthy red blood cells to carry adequate oxygen to your tissues
Leukopenia
Shortage of white blood cells
Thrombocytopenia
disorder in which there are not enough platelets

8. Red Blood Cells Erythrocytes Hemoglobin Erythropoietin
million/microliter
Transports protein
Hemoglobin
Large protein molecule, contains iron, carries oxygen
Erythropoietin
glycoprotein hormone, stimulates the production of red blood cells

9. White Blood Cells Leukocytes Neutrophil Basophil Eosinophil
5-10 thousand/microliter
Phagocytosis
leukocytosis
Neutrophil
Basophil
Eosinophil

10. Platelets Thrombocytes 150-450 thousand/microliter Life span 5-9 days
Prevents blood loss

11. Complete Blood Count
RBC’s
WBC’s
Platelets
Hgb
Hct

12. Differential Count
The percentage of each of the five different types of WBC’s are measured

13. Hemostasis Blood Vessels Spasm Formation of a Platelet Plug
Blood Clotting

14. Blood Types & Rh Factor A B AB O
Positive +
Negative -

15. Lymphatic System

16. Lymph
Clear fluid that consist of:
Water
Electrolytes
Waste
Proteins

17. Lymphatic Vessels Capillaries Lymphatic Ducts Right Lymphatic Duct
Thoracic Duct

18. Lymphoid Organs
Lymph Nodes
Tonsils
Thymus Gland
Spleen

19. Nodes vs Vessels

21. Immune System

22. Classifications Nonspecific Immunity Specific Immunity
Does not distinguish between pathogens and nonpathogens or invading material- it reacts to all of these to the same extent
Specific Immunity
Protects us against specific nonself organisms and substances. It is an induced response; that is it must be taught which things to attack.

23. Types of Immunity Genetic Immunity Acquired Immunity
immunity is present prior to the exposure to a pathogen (species immunity – humans do not get parvo)
Acquired Immunity
it requires previous exposure to a pathogen (or its product) before immunity is acquired by the host

24. Immunologic Responses
Allergic Reactions

25. Immune Responses (cont:)
Autoimmune Disease
The body produces antibodies towards itself
Organ Rejection
Transplant rejection is when a transplant recipient's immune system attacks a transplanted organ or tissue