Presentation is loading. Please wait.

Presentation is loading. Please wait.

Nonaggressive systemic mastocytosis (SM) without skin lesions associated with insect- induced anaphylaxis shows unique features versus other indolent SM 

Similar presentations


Presentation on theme: "Nonaggressive systemic mastocytosis (SM) without skin lesions associated with insect- induced anaphylaxis shows unique features versus other indolent SM "— Presentation transcript:

1 Nonaggressive systemic mastocytosis (SM) without skin lesions associated with insect- induced anaphylaxis shows unique features versus other indolent SM  Iván Álvarez-Twose, MD, Roberta Zanotti, MD, David González-de-Olano, MD, Patrizia Bonadonna, MD, Arantza Vega, MD, Almudena Matito, MD, Laura Sánchez-Muñoz, MD, PhD, José Mário Morgado, MSc, Omar Perbellini, MD, Andrés García-Montero, PhD, Giovanna De Matteis, MD, Cristina Teodósio, MSc, Maurizio Rossini, MD, María Jara-Acevedo, MSc, Donatella Schena, MD, Andrea Mayado, PhD, Alberto Zamò, MD, Manuela Mollejo, MD, PhD, Paula Sánchez-López, MD, Nieves Cabañes, MD, Alberto Orfao, MD, PhD, Luis Escribano, MD, PhD Iván Álvarez-Twose, MD, Roberta Zanotti, MD, David González-de-Olano, MD, Patrizia Bonadonna, MD, Arantza Vega, MD, Almudena Matito, MD, Laura Sánchez-Muñoz, MD, PhD, José Mário Morgado, MSc, Omar Perbellini, MD, Andrés García- Montero, PhD, Giovanna De Matteis, MD, Cristina Teodósio, MSc, Maurizio Rossini, MD, María Jara-Acevedo, MSc, Donatella Schena, MD, Andrea Mayado, PhD, Alberto Zamò, MD, Manuela Mollejo, MD, PhD, Paula Sánchez-López, MD, Nieves Cabañes, MD, Alberto Orfao, MD, PhD, Luis Escribano, MD, PhD  Journal of Allergy and Clinical Immunology  Volume 133, Issue 2, Pages e5 (February 2014) DOI: /j.jaci Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2 Fig 1 Distribution of clinical symptoms associated with the most severe MC-mediator release episode (A) and in between acute episodes (B) in patients with insectISMs− (n = 143) versus otherISMs− cases (n = 72) and ISMs+ patients (n = 56). Only clinical symptoms showing statistically significant differences (P < .05) among the different groups of patients are shown (A). GI, Gastrointestinal; NS, statistically not significant. Journal of Allergy and Clinical Immunology  , e5DOI: ( /j.jaci ) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

3 Fig E1 Distribution of different triggers involved in acute MC-mediator release episodes in patients with insectISMs− (n = 143) (A), otherISMs− (n = 72) (B), ISMs+ (n = 56) (C), and nonclonal MCAS (n = 64) (D). Black boxes indicate the specific trigger(s) for MC-mediator release episodes involved in every case, and striped boxes represent those fish-triggered cases in which hypersensitivity to Anisakis simplex was found by CAP and/or skin tests. Journal of Allergy and Clinical Immunology  , e5DOI: ( /j.jaci ) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

4 Fig E1 Distribution of different triggers involved in acute MC-mediator release episodes in patients with insectISMs− (n = 143) (A), otherISMs− (n = 72) (B), ISMs+ (n = 56) (C), and nonclonal MCAS (n = 64) (D). Black boxes indicate the specific trigger(s) for MC-mediator release episodes involved in every case, and striped boxes represent those fish-triggered cases in which hypersensitivity to Anisakis simplex was found by CAP and/or skin tests. Journal of Allergy and Clinical Immunology  , e5DOI: ( /j.jaci ) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

5 Fig E1 Distribution of different triggers involved in acute MC-mediator release episodes in patients with insectISMs− (n = 143) (A), otherISMs− (n = 72) (B), ISMs+ (n = 56) (C), and nonclonal MCAS (n = 64) (D). Black boxes indicate the specific trigger(s) for MC-mediator release episodes involved in every case, and striped boxes represent those fish-triggered cases in which hypersensitivity to Anisakis simplex was found by CAP and/or skin tests. Journal of Allergy and Clinical Immunology  , e5DOI: ( /j.jaci ) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

6 Fig E1 Distribution of different triggers involved in acute MC-mediator release episodes in patients with insectISMs− (n = 143) (A), otherISMs− (n = 72) (B), ISMs+ (n = 56) (C), and nonclonal MCAS (n = 64) (D). Black boxes indicate the specific trigger(s) for MC-mediator release episodes involved in every case, and striped boxes represent those fish-triggered cases in which hypersensitivity to Anisakis simplex was found by CAP and/or skin tests. Journal of Allergy and Clinical Immunology  , e5DOI: ( /j.jaci ) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions


Download ppt "Nonaggressive systemic mastocytosis (SM) without skin lesions associated with insect- induced anaphylaxis shows unique features versus other indolent SM "

Similar presentations


Ads by Google