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Battling the Flu: Latest Advances in the Influenza Treatment Arsenal

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Presentation on theme: "Battling the Flu: Latest Advances in the Influenza Treatment Arsenal"— Presentation transcript:

1 Battling the Flu: Latest Advances in the Influenza Treatment Arsenal

2 Influenza Is a Serious Public Health Burden 2017-2018 Flu Season Was Unusually Severe

3 Vaccination Rates for Influenza Among Adults Decreased in 2017-2018

4 Influenza Antiviral Drugs Are an Important Adjunct to Vaccination

5 Commercially Available Antiviral Agents for Treatment and Prevention of Influenza in the United States

6 Neuraminidase Inhibitors Mechanism of Action

7 Oseltamivir

8 Oseltamivir Safety

9 Zanamivir

10 Peramivir

11 Viral Resistance to Neuraminidase Inhibitors: How Big a Problem?

12 Novel Antiviral Influenza Therapy: Baloxavir

13 Phase 3 Study of Baloxavir for Uncomplicated Influenza in Adults and Adolescents

14 Phase 3 Study of Baloxavir Efficacy

15 Phase 3 Study of Baloxavir Change in Influenza Infectious Viral Load

16 Phase 3 Study of Baloxavir Adverse Events

17 Resistance to Baloxavir in the Phase 3 Trial

18 Emerging Influenza Antiviral Agents

19 Who Should Get Influenza Antiviral Therapy?

20 High-Risk Patients

21 Practical Considerations for Influenza Antiviral Therapy

22 Concluding Remarks

23 Concluding Remarks (cont)

24 Abbreviations


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