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Edwin A. Bronsky, MD, Howard Druce, MD, Steven R. Findlay, MD, Frank C

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Presentation on theme: "Edwin A. Bronsky, MD, Howard Druce, MD, Steven R. Findlay, MD, Frank C"— Presentation transcript:

1 A clinical trial of ipratropium bromide nasal spray in patients with perennial nonallergic rhinitis 
Edwin A. Bronsky, MD, Howard Druce, MD, Steven R. Findlay, MD, Frank C. Hampel, MD, Harold Kaiser, MD, Paul Ratner, MD, Martin D. Valentine, MD, Chester C. Wood, MD  Journal of Allergy and Clinical Immunology  Volume 95, Issue 5, Pages (May 1995) DOI: /S (95) Copyright © 1995 Mosby, Inc. Terms and Conditions

2 FIG. 1 Adjusted mean change in rhinorrhea during 8 weeks of treatment. The combined measure was a weighted average of duration and severity. Journal of Allergy and Clinical Immunology  , DOI: ( /S (95) ) Copyright © 1995 Mosby, Inc. Terms and Conditions

3 FIG. 1 Adjusted mean change in rhinorrhea during 8 weeks of treatment. The combined measure was a weighted average of duration and severity. Journal of Allergy and Clinical Immunology  , DOI: ( /S (95) ) Copyright © 1995 Mosby, Inc. Terms and Conditions

4 FIG. 1 Adjusted mean change in rhinorrhea during 8 weeks of treatment. The combined measure was a weighted average of duration and severity. Journal of Allergy and Clinical Immunology  , DOI: ( /S (95) ) Copyright © 1995 Mosby, Inc. Terms and Conditions

5 FIG. 2 Proportion of patients with symptoms who believed the trial medication provided either "good" or "excellent" control of rhinorrhea. Journal of Allergy and Clinical Immunology  , DOI: ( /S (95) ) Copyright © 1995 Mosby, Inc. Terms and Conditions

6 FIG. 3 Reduction in the degree to which rhinorrhea interfered with daily activities and moods; percentage of patients experiencing a significant improvement in quality of life (i.e., interference none or title of the time). Journal of Allergy and Clinical Immunology  , DOI: ( /S (95) ) Copyright © 1995 Mosby, Inc. Terms and Conditions

7 FIG. 4 Absence of nasal rebound on cessation of treatment with ipratropium bromide nasal spray. Journal of Allergy and Clinical Immunology  , DOI: ( /S (95) ) Copyright © 1995 Mosby, Inc. Terms and Conditions

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