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Gestational Diabetes: Glycemic Control in the Last Two Weeks Before Delivery Contributes to Newborn Insulinemia  Pablo R. Olmos, MD, Gisella R. Borzone,

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Presentation on theme: "Gestational Diabetes: Glycemic Control in the Last Two Weeks Before Delivery Contributes to Newborn Insulinemia  Pablo R. Olmos, MD, Gisella R. Borzone,"— Presentation transcript:

1 Gestational Diabetes: Glycemic Control in the Last Two Weeks Before Delivery Contributes to Newborn Insulinemia  Pablo R. Olmos, MD, Gisella R. Borzone, MD, PhD, Andrés Poblete, MD  Journal of Obstetrics and Gynaecology Canada   Volume 40, Issue 11, Pages (November 2018) DOI: /j.jogc Copyright © 2018 Society of Obstetricians and Gynaecologists of Canada Terms and Conditions

2 Figure 1 (A) Fetal insulinemia throughout the second half of pregnancy can accelerate fetal growth. (B) Fetal insulinemia at delivery, with its potential effects on neonatal hypoglycemia and hyperbilirubinemia. Although umbilical cord C-peptide reflects recent fetal insulin secretion, little is known about what “recent” means with regard to delivery (see the text). Journal of Obstetrics and Gynaecology Canada   , DOI: ( /j.jogc ) Copyright © 2018 Society of Obstetricians and Gynaecologists of Canada Terms and Conditions

3 Figure 2 Correlations between maternal HbA1c and fetal umbilical cord blood C-peptide at birth, at two time points in GDM pregnancies: (A) at an early visit (32.95 ± 1.8 weeks), and (B) at the last (35.04 ± 1.6 weeks). Correlation is statistically significant only at the last visit. Journal of Obstetrics and Gynaecology Canada   , DOI: ( /j.jogc ) Copyright © 2018 Society of Obstetricians and Gynaecologists of Canada Terms and Conditions

4 Figure 3 Correlations between maternal mean glucose (MBG, mmol/L) and fetal umbilical cord blood C-peptide at birth, at two time points in GDM pregnancies: (A) at an early visit (32.95 ± 1.8 weeks), and (B) at the last visit (35.04 ± 1.6 weeks). Correlation is statistically significant only at the last visit. Journal of Obstetrics and Gynaecology Canada   , DOI: ( /j.jogc ) Copyright © 2018 Society of Obstetricians and Gynaecologists of Canada Terms and Conditions

5 Journal of Obstetrics and Gynaecology Canada  2018 40, 1445-1452DOI: (10.1016/j.jogc.2018.01.026)
Copyright © 2018 Society of Obstetricians and Gynaecologists of Canada Terms and Conditions


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