1. Efficacy and safety of praziquantel in preschool-aged and school-aged children infected with Schistosoma mansoni: a randomised controlled, parallel-group, dose-ranging, phase 2 trial 
Jean T Coulibaly, PhD, Gordana Panic, PhD, Kigbafori D Silué, PhD, Jana Kovač, MSc, Jan Hattendorf, PhD, Prof Jennifer Keiser, PhD 
The Lancet Global Health 
Volume 5, Issue 7, Pages e688-e698 (July 2017)
DOI: /S X(17)
Copyright © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Terms and Conditions

2. Figure 1
Trial profile
PSAC=preschool-aged children. SAC=school-aged children. S mansoni=Schistosomiasis mansoni.
The Lancet Global Health 2017 5, e688-e698DOI: ( /S X(17) )
Copyright © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Terms and Conditions

3. Figure 2 Cure rates in PSAC (blue lines) and SAC (red lines)
Circles show observed cure rates with 95% CIs (vertical lines). Numbers and colour code in the circles show geometric mean infection intensities at baseline (BL). Dashed lines represent the estimated dose–response curve and corresponding 95% confidence bands predicted by the Emax models. Epg=eggs per gram of stool. PSAC=preschool-aged children. SAC=school-aged children.
The Lancet Global Health 2017 5, e688-e698DOI: ( /S X(17) )
Copyright © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Terms and Conditions

4. Figure 3 Egg reduction rates in PSAC (blue lines) and SAC (red lines)
Diamonds show observed cure rates with 95% CIs (vertical lines). Dashed lines represent the estimated dose response curve and corresponding 95% confidence bands predicted by the Emax model. PSAC=preschool-aged children. SAC=school-aged children.
The Lancet Global Health 2017 5, e688-e698DOI: ( /S X(17) )
Copyright © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Terms and Conditions