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Cerebral Organoids in a Dish: Progress and Prospects

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1 Cerebral Organoids in a Dish: Progress and Prospects
Marina Bershteyn, Arnold R. Kriegstein  Cell  Volume 155, Issue 1, Pages (September 2013) DOI: /j.cell Copyright © 2013 Elsevier Inc. Terms and Conditions

2 Figure 1 Generation of 3D Endodermal and Ectodermal Organoids from Skin Fibroblasts Reprogramming of fibroblasts into induced pluripotent stem cells (iPSCs) enables in vitro differentiation into tissue-specific progenitors, such as intestinal stem cells, thyroid, or neuroectodermal progenitors. When grown under the right conditions in suspension, these progenitors self-organize into 3D tissues resembling the intestine, thyroid, optic cup, or cerebral cortex. Cell  , 19-20DOI: ( /j.cell ) Copyright © 2013 Elsevier Inc. Terms and Conditions


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