1. Sit at same seats from last week (no move)
Opening Activity: May 15, 2018
Sit at same seats from last week (no move)
Fill out protein production portion of your idea journal.
Pick up Gene Regulation Reading at front table.
Pick up Gene Regulation notes – tape in.
Read the handout
Answer the 3 questions on the bottom in journal.
I can… Explain how gene regulation is related to the recovery of c. elegans worms on high salt plates.
Homework:
Review source, which items are missing – get in!!
Gene Regulation Test 5/22

2. How can cells have the same DNA but different sets of proteins?
Gene expression refers to the genes being translated into proteins in a cell
In a given cell, some genes are “on” while other genes are “off”. Different cells express different sets of genes.

3. How are Genes Regulated?
Coding region – the part of the DNA with specific information to build a protein
Regulatory region – sequence of DNA that can be bound by a protein to regulate gene expression
Regulatory protein that binds to to in order to turn transcription on or off
Indicate where the regulatory DNA is compared to the coding sequence.
Regulatory Protein
Regulatory Region
Coding Sequence

4. How are Genes Regulated?
Coding region – the part of the DNA with specific information to build a protein
Regulatory region – sequence of DNA that can be bound by a protein to regulate gene expression
Regulatory protein that binds to to in order to turn transcription on or off
Indicate where the regulatory DNA is compared to the coding sequence.

5. How are Regulatory Proteins Turned On?
Regulatory proteins are turned ON or OFF by signals detected by the cell
Signals can be…
Hormones
Sunlight
Food
???
Indicate where the regulatory DNA is compared to the coding sequence.
Regulatory Protein
Regulatory Region
Coding Sequence

6. Today’s Work
Regulatory
Protein
Regulatory DNA Sequence
AGATCAGC
TCTAGTCG
CGACTCAC
GCTGAGTG
TAGACTCC
ATCTGAGG
GAGCTACG
CTCGATGC
ATGCCTGC
TACGGACG
Complete the Gene Regulation Activity in your journal for a STAMP.
Finish other journal work.
Regulatory proteins in cell
CELL #1
Which proteins are made?
gene C is transcribed, RNA is translated, protein C is made
Protein C
GAGCTACG
CTCGATGC
Coding sequence gene A
Coding sequence gene B
Coding sequence gene C
ATGCCTGC
TACGGACG
AGATCAGC
TCTAGTCG

7. How do worms recover from environmental changes?
With your partners at your table to complete the worm handout. DUE TODAY!

8. What is a the role of a coding region on DNA?
May 17, 2018
What is a the role of a coding region on DNA?
How does a regulatory protein activate a gene to be turned “on”?
I can… Create an explanation for how the worms recovered on the high salt plates.
Homework:
Review source, which items are missing – get in!!
Gene Regulation Test 5/24

9. How do worms recover from environmental changes?
With your lab group write out the story for how the worms recovered from the high salt environment. Use pictures/diagrams when useful.
Example:
Step 1 – Worms on low salt plates moved freely, eating, reproducing and moved in a shape.
Step 2 – Worms “chunked” on high salt plates…….
Step 3 - …

10. Today’s Goals
How do worms recover from environmental changes? Work time for worm explanation – DUE TODAY!
Pick up Gene Regulation Unit Checklist, NB & Review – Reflection & Review due Tuesday 4/22
Review checklist and complete
Update notebook
Complete vocabulary
Work with a team of students to write a biomolecular pathway for the Blue People of Troublesome Creek (get handout from Ms. Fox).

11. The Blue People of Troublesome Creek
Read (pg. 147) complete analysis questions pg. 151
How do you think DNA, proteins and traits are related to blue people?
Create a biomolecular model for a blue person and non-blue person cell
Another ex. Pg 459 in
Blue AHA Book.