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Figure. Patient imaging

Published bySudirman Indradjaja Modified over 5 years ago

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1 Figure. Patient imaging
Patient imaging (A, B) CT scan shows a tumor with calcifications and fatty tissue inferior to the left thyroid gland (arrows). (C) Histologic analysis reveals a mature teratoma containing cartilage, fatty tissue, glands, and hair follicles. (D) Some areas contained dense lymphocyte infiltrates, which are common in NMDA receptor encephalitis–associated teratomas.3 (E) Atypical neuronal elements in the teratoma detected with NeuN immunohistochemistry. (F, G) A similar neuronal staining was seen when sections were incubated with either a commercial anti-NR1 antibody (F) or CSF of a patient with high-titer NMDAR antibodies after immunoglobulin fluorescence labeling (G). For this, CSF was conjugated with N-hydroxysuccinimide-ester of Alexa Fluor 594 (Life Technologies, Carlsbad, CA) as described previously.2 Tania Kümpfel et al. Neurol Neuroimmunol Neuroinflamm 2016;3:e250 © 2016 American Academy of Neurology

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