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Bashir M Matata, PhD, Andrzej W Sosnowski, MD, Manuel Galiñanes 

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Presentation on theme: "Bashir M Matata, PhD, Andrzej W Sosnowski, MD, Manuel Galiñanes "— Presentation transcript:

1 Off-pump bypass graft operation significantly reduces oxidative stress and inflammation 
Bashir M Matata, PhD, Andrzej W Sosnowski, MD, Manuel Galiñanes  The Annals of Thoracic Surgery  Volume 69, Issue 3, Pages (March 2000) DOI: /S (99)

2 Fig 1 Changes in plasma levels of complement (A) C3a, (B) elastase, and (C) blood leukocyte count before, during, and after coronary bypass graft operation, performed with or without cardiopulmonary bypass (CPB). Values are expressed as means of 10 patients per group, and bars represent the standard error of mean. ∗p less than 0.05 versus prior anesthesia (PA) values within the same group. †p less than 0.05 versus the corresponding value of the non CPB group. The Annals of Thoracic Surgery  , DOI: ( /S (99) )

3 Fig 2 Changes in plasma levels of (A) IL-8 and (B) TNF-α before, during, and after coronary bypass graft surgery performed with or without cardiopulmonary bypass (CPB). Values are expressed as means of 10 patients per group, and bars represent the standard error of mean. ∗p less than 0.05 versus prior anesthesia (PA) values within the same group. †p less than 0.05 versus the corresponding value of the non CPB group. The Annals of Thoracic Surgery  , DOI: ( /S (99) )

4 Fig 3 Changes in plasma levels of (A) lipid hydroperoxides, (B) protein carbonyls, and (C) protein nitrotyrosine before, during, and after coronary bypass graft operation with or without cardiopulmonary bypass (CPB). Values are expressed as means of 10 patients per group, and bars represent the standard error of mean. ∗p less than 0.05 versus prior anesthesia (PA) values within the same group. †p less than 0.05 versus the corresponding value of the non CPB group. The Annals of Thoracic Surgery  , DOI: ( /S (99) )

5 Fig 4 Changes in plasma levels of (A) soluble E-selectin and (B) thrombomodulin concentrations before, during, and after coronary bypass graft operation with or without cardiopulmonary bypass (CPB). Values are expressed as means of 10 patients per group, and bars represent the standard error of mean. ∗p less than 0.05 versus prior anesthesia (PA) values within the same group. The Annals of Thoracic Surgery  , DOI: ( /S (99) )

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