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David J. Cousins, PhD, Joanne McDonald, BSc, Tak H. Lee, MD, ScD 

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Presentation on theme: "David J. Cousins, PhD, Joanne McDonald, BSc, Tak H. Lee, MD, ScD "— Presentation transcript:

1 Therapeutic approaches for control of transcription factors in allergic disease 
David J. Cousins, PhD, Joanne McDonald, BSc, Tak H. Lee, MD, ScD  Journal of Allergy and Clinical Immunology  Volume 121, Issue 4, Pages (April 2008) DOI: /j.jaci Copyright © 2008 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2 Fig 1 Transcription factor signaling pathways in allergic disease. A schematic diagram detailing the signaling pathways and the points at which therapeutic interventions have been targeted is shown. Thin lines represent steps in the signaling cascade. Thick lines represent therapeutic strategies that have been examined to date. Please refer to the text for detailed descriptions. TCR, T-cell receptor; AS-ODN, antisense oligodeoxynucleotide; NBD, NF-κB essential modulator binding domain; Hsp, heat shock protein; p65/p50, subunits of NF-κB. Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2008 American Academy of Allergy, Asthma & Immunology Terms and Conditions


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