1. Association Between Serum Level of Hepatitis B Surface Antigen at End of Entecavir Therapy and Risk of Relapse in E Antigen–Negative Patients 
Yao-Chun Hsu, Lein-Ray Mo, Chi-Yang Chang, Ming-Shiang Wu, Jia-Horng Kao, Wen-Lun Wang, Tzeng-Huey Yang, Chaur-Shine Wang, Ming-Feng Chiang, Chieh-Chang Chen, Yu-Jen Fang, Hsu-Wei Hung, Chun-Ying Wu, Jaw-Town Lin 
Clinical Gastroenterology and Hepatology 
Volume 14, Issue 10, Pages e3 (October 2016)
DOI: /j.cgh
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2. Figure 1
Significant dose-response association between EOT HBsAg level and clinical (A) and virologic (B) relapse in patients with negative HBeAg at the end of treatment.
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3. Figure 2
Age-adjusted stratified analyses for the association of end-of-therapy HBsAg with clinical (A) and virologic (B) relapses.
Clinical Gastroenterology and Hepatology  , e3DOI: ( /j.cgh )
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4. Figure 3
HBsAg cutoff set at 10 IU/mL (A for clinical, B for virologic) and 100 IU/mL (C for clinical, D for virologic) to stratify relapse risks.
Clinical Gastroenterology and Hepatology  , e3DOI: ( /j.cgh )
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5. Supplementary Figure 1
Flowchart illustrating identification and enrollment of participants.
Clinical Gastroenterology and Hepatology  , e3DOI: ( /j.cgh )
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6. Supplementary Figure 2
The risk of relapse significantly differed according to HBeAg status at the end of therapy. Panel A (left), clinical relapse; panel B (right), virological relapse.
Clinical Gastroenterology and Hepatology  , e3DOI: ( /j.cgh )
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7. Supplementary Figure 3
Extremely high relapse risks regardless of HBsAg levels in patients who remained HBeAg-positive at the end of therapy. Panel A (left), clinical relapse; panel B (right), virological relapse.
Clinical Gastroenterology and Hepatology  , e3DOI: ( /j.cgh )
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8. Supplementary Figure 4 Age was inversely correlated with HBsAg levels.
Clinical Gastroenterology and Hepatology  , e3DOI: ( /j.cgh )
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9. Supplementary Figure 5
Similar relapse patterns in end-of-therapy HBeAg-negative patients irrespective of their pretreatment HBeAg status. Panel A (left), clinical relapse; panel B (right), virological relapse.
Clinical Gastroenterology and Hepatology  , e3DOI: ( /j.cgh )
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