1. Genesis 1:26
26 And God said, Let us make man in our image, after our likeness: and let them have dominion over the fish of the sea, and over the fowl of the air, and over the cattle, and over all the earth, and over every creeping thing that creepeth upon the earth.

2. DNA Technology
Timothy G. Standish, Ph. D.

3. What is DNA Technology?
Technology = The application of science in industry and/or commerce.
Because DNA is the genetic material, manipulation of DNA (genetic engineering) allows the modification of organisms in such a way that they are more valuable than they were in their natural state.

4. Products of DNA Technology
Recombinant organisms - Some examples:
Herbicide-resistant soybeans
Super tomatoes
Natural products produced by recombinant organisms:
Humulin - Human insulin produced in cell culture
Tissue Plasminogen Activator (TPA)
Engineered products produced by recombinant organisms:
Amplitaque - A modified DNA polymerase
Information:
Genetic testing for identification of diseases, individuals etc...
DNA sequencing

5. A Short History 1869 - Miescher isolated DNA for the first time
Avery et al. provided evidence that DNA is the genetic material
Watson and Crick described the double helix structure of DNA
Kornberg discovered DNA polymerase
Marmer and Doty discovered DNA renaturation
Arber, Nathans and Smith discovered restriction endonucleases
Nirenberg, Ochoa, and Khorana figured out the genetic code.

6. A Short History Cont. 1967 - Geller discovered DNA ligase
Boyer, Cohen and Berg develop DNA cloning techniques
Southern developed gel-transfer hybridization
Sanger and Barrel and Maxam and Gilbert developed DNA sequencing methods
Palmiter and Brinster produced transgenic mice, Spradling and Rubin produced transgenic fruit flies
Mullis and colleagues invented the Polymerase Chain Reaction (PCR)

7. and grow up bacteria with clone of interest
Strategy
Extract DNA
Fragment DNA
Insert into vector
DNA Library in bacteria
Screen library
and grow up bacteria with clone of interest

8. The
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