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Meghan Campo, MD, David Gerber, MD, Justin F. Gainor, MD, Rebecca S

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Presentation on theme: "Meghan Campo, MD, David Gerber, MD, Justin F. Gainor, MD, Rebecca S"— Presentation transcript:

1 Acquired Resistance to First-Line Afatinib and the Challenges of Prearranged Progression Biopsies 
Meghan Campo, MD, David Gerber, MD, Justin F. Gainor, MD, Rebecca S. Heist, MD, MPH, Jennifer S. Temel, MD, Alice T. Shaw, MD, PhD, Panos Fidias, MD, Alona Muzikansky, Jeffrey A. Engelman, MD, PhD, Lecia V. Sequist, MD, MPH  Journal of Thoracic Oncology  Volume 11, Issue 11, Pages (November 2016) DOI: /j.jtho Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

2 Figure 1 Individual patient response to treatment. Colored bars represent the magnitude of each patient’s response to afatinib compared with baseline tumor burden with type of EGFR mutation noted. RECIST, Response Evaluation Criteria in Solid Tumors. Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

3 Figure 2 CONSORT diagram. Flow of patients who consented to repeat biopsy. pts, patients; pt, patient; PD, progressive disease; AR, acquired resistance; CNS, central nervous system. Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

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