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A randomized, controlled, pilot trial on the effect of dehydroepiandrosterone on ovarian response markers, ovarian response, and in vitro fertilization.

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Presentation on theme: "A randomized, controlled, pilot trial on the effect of dehydroepiandrosterone on ovarian response markers, ovarian response, and in vitro fertilization."— Presentation transcript:

1 A randomized, controlled, pilot trial on the effect of dehydroepiandrosterone on ovarian response markers, ovarian response, and in vitro fertilization outcomes in poor responders  Tracy Wing Yee Yeung, M.B., B.S., Joyce Chai, M.B., Ch.B., Raymond Hang Wun Li, M.B., B.S., Vivian Chi Yan Lee, M.B., B.S., Pak Chung Ho, M.D., Ernest Hung Yu Ng, M.D.  Fertility and Sterility  Volume 102, Issue 1, Pages e1 (July 2014) DOI: /j.fertnstert Copyright © 2014 American Society for Reproductive Medicine Terms and Conditions

2 Figure 1 Box-and-whisker plots of ovarian response markers (AFC, AMH, FSH), serum estradiol (E2), DHEA-S, testosterone, SHBG, and FAI (free androgen index) for women randomized into DHEA (shaded box) or placebo (open box) groups. Boxes indicate 25th and 75th percentiles, with the horizontal line representing the median values. Whiskers span the range between the 5th and the 95th percentiles of the data. The x-axis represents the time of the blood draw after DHEA/placebo use. FAI was defined as the total testosterone/SHBG (both in nmol/L) × 100. ∗Statistically significant difference (P<.05). Fertility and Sterility  , e1DOI: ( /j.fertnstert ) Copyright © 2014 American Society for Reproductive Medicine Terms and Conditions

3 Figure 2 Box-and-whisker plots of follicular fluid hormone concentrations for women randomized into DHEA (shaded box) or placebo (open box) groups. Boxes indicate 25th and 75th percentiles, with the horizontal line representing the median values. Whiskers span the range between the 5th and the 95th percentiles of the data. ∗Statistically significant difference (P<.05). Fertility and Sterility  , e1DOI: ( /j.fertnstert ) Copyright © 2014 American Society for Reproductive Medicine Terms and Conditions

4 Supplemental Figure 1 CONSORT 2010 flow diagram.
Fertility and Sterility  , e1DOI: ( /j.fertnstert ) Copyright © 2014 American Society for Reproductive Medicine Terms and Conditions


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