1. Figure 1 Distinct features of adipocytes
Figure 1 | Distinct features of adipocytes. Three types of adipocytes are generally found in rodents and humans. White adipocytes have few mitochondria and high lipid content; they store energy in the form of triglycerides. Brown adipocytes contain a high amount of mitochondria and mitochondrial brown fat uncoupling protein 1 (UCP1), which uncouples ATP generation and thus dissipates energy as heat. Beige adipocytes contain rather high mitochondrial activity and UCP1 and thus contribute to thermogenesis. Cold exposure or β-adrenergic (βAR) stimuli induce beige adipogenesis, either from de novo adipogenesis or transdifferentiation of white adipocytes, a biological process referred to as 'beiging'. In addition, beige adipocytes can revert back to white adipocytes under obesogenic conditions in a reverse process referred to as 'whitening'. CKD, chronic kidney disease.
Zhu, Q. & Scherer, P. E. (2017) Immunologic and endocrine functions of adipose tissue: implications for kidney disease
Nat. Rev. Nephrol. doi: /nrneph