1. Cellular Respiration Part 2
AP Biology
Cellular Respiration
Part 2

2. Is Oxygen present?

3. Pyruvate Conversion CYTOSOL MITOCHONDRION NAD+ NADH + H+ Acetyl Co A
Coenzyme A
Transport protein

4. Kreb’s Cycle Simplified

5. Actual Kreb’s Cycle

6. Electron Transport Chain is located on the inner FOLDED membrane

7. Electron Transport Chain (Proteins are H+ Pumps)

8. “Building” the proton concentration gradient
Inner
mitochondrial
membrane
Citric
acid
cycle
Oxidative
phosphorylation:
electron transport
and chemiosmosis
Glycolysis
ATP
ATP
ATP H+ H+ H+ H+
Protein complex
of electron
carriers
Cyt c
Intermembrane
space Q IV I
III
ATP
synthase
Inner
mitochondrial
membrane II
2H+ + 1/2 O2
H2O
FADH2
FAD
NADH
+ H+
NAD+
ADP + P
ATP i
(carrying electrons
from food) H+
Mitochondrial
matrix
Electron transport chain
Electron transport and pumping of protons (H+),
Which create an H+ gradient across the membrane
Chemiosmosis
ATP synthesis powered by the flow
of H+ back across the membrane
Oxidative phosphorylation

9. ATP Synthetase Complex using kinetic movement of H+ (protons)