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The pregnancy associated protein glycodelin as a follow-up biomarker in a male non- small cell lung cancer patient  Marc A. Schneider, Nicolas C. Kahn,

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Presentation on theme: "The pregnancy associated protein glycodelin as a follow-up biomarker in a male non- small cell lung cancer patient  Marc A. Schneider, Nicolas C. Kahn,"— Presentation transcript:

1 The pregnancy associated protein glycodelin as a follow-up biomarker in a male non- small cell lung cancer patient  Marc A. Schneider, Nicolas C. Kahn, Michael Thomas, Felix J.F. Herth, Thomas Muley, Claus P. Heussel, Michael Meister, Hendrik Dienemann  Cancer Treatment and Research Communications  Volume 4, Pages (January 2015) DOI: /j.ctrc Copyright © 2015 Elsevier Ltd Terms and Conditions

2 Fig. 1 CT scans. Contrast enhanced CT scans show establishing of a metastasis in the left upper lobe (A)–(D) and recurrence or progression disease after anew surgery (E), respectively. Cancer Treatment and Research Communications 2015 4, DOI: ( /j.ctrc ) Copyright © 2015 Elsevier Ltd Terms and Conditions

3 Fig. 2 Glycodelin gene and protein expression in the tumor. (A) The expression of the glycodelin gene (PAEP) was determined by qPCR in tumor and corresponding normal lung tissue. Please note that a high Ct value means a low gene expression. (B) Glycodelin protein was stained in primary tumor, in metastatic disease and in affected lymph node by immunohistochemistry. Cancer Treatment and Research Communications 2015 4, DOI: ( /j.ctrc ) Copyright © 2015 Elsevier Ltd Terms and Conditions

4 Fig. 3 Glycodelin serum concentrations. The glycodelin serum level was measured before treatment of the patient (WR1) and during follow-up (WR2-6). WR=ward round, M=metastatic disease,+=tumor dependent death. Cancer Treatment and Research Communications 2015 4, DOI: ( /j.ctrc ) Copyright © 2015 Elsevier Ltd Terms and Conditions

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