1. Krebs Cycle

2. Krebs Cycle

3. Krebs Cycle Overview Krebs cycle is a cyclical process to:
Also known as the citric acid cycle and the tricarboxylic acid cycle (TCA).

4. Krebs Cycle

5. Krebs Cycle: Step by Step
join 2 carbon molecule with a 4 carbon molecule
rxn type:
enzyme:
energy:

6. Krebs Cycle: Step by Step
rearrangement of atoms with the help of H2O
rxn type:
enzyme:
energy:

7. Krebs Cycle: Step by Step
synthesis of CO2 and NADH
rxn type:
enzyme:
energy:

8. Krebs Cycle: Step by Step
CO2 release and energy molecule formation
rxn type:
enzyme:
energy:

9. Krebs Cycle: Step by Step
ADP phosphorylation to ATP
rxn type:
enzyme:
energy:

10. Krebs Cycle: Step by Step
FADH2 (energy molecule) formation
rxn type:
enzyme:
energy:

11. FAD / FADH2 FAD – flavin adenine dinucleotide (oxidized form)
FADH2 – flavin adenine dinucleotide (reduced form)

12. Krebs Cycle: Step by Step
rearranging the molecule for the next reaction
rxn type:
enzyme:
energy:

13. Krebs Cycle: Step by Step
energy molecule formation & recreating molecules for Krebs cycle
rxn type:
enzyme:
energy:

14. Krebs Cycle Summary two cycles of Krebs for EACH glucose molecule
acetyl-CoA  oxaloacetate (per cycle)
___ CO2 released (per cycle)
___ NADH produced (per cycle)
___ FADH2 produced (per cycle)
___ ATP produced (per cycle)

15. Krebs Cycle: Big Picture Perspective
Many of the components of Krebs cycle are used in many other types of metabolic processes.