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Developmental ERK Signaling Goes Digital

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1 Developmental ERK Signaling Goes Digital
Coralie Dessauges, Olivier Pertz  Developmental Cell  Volume 42, Issue 5, Pages (September 2017) DOI: /j.devcel Copyright © 2017 Elsevier Inc. Terms and Conditions

2 Figure 1 Converting a Graded into a Digital Signal
As a consequence of their distinct spatial locations, each of the five VPCs perceives a different level of EGF released from the anchor cell (AC). In response, the VPCs display ERK activity of fixed amplitude and duration but with different frequencies, corresponding to their location in the EGF morphogen gradient. Developmental Cell  , DOI: ( /j.devcel ) Copyright © 2017 Elsevier Inc. Terms and Conditions

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