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Verotoxin biology: molecular events in vascular endothelial injury

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Presentation on theme: "Verotoxin biology: molecular events in vascular endothelial injury"— Presentation transcript:

1 Verotoxin biology: molecular events in vascular endothelial injury
Tania N Petruzziello, Imtiaz A Mawji, Mukarram Khan, Philip A Marsden  Kidney International  Volume 75, Pages S17-S19 (February 2009) DOI: /ki Copyright © 2009 International Society of Nephrology Terms and Conditions

2 Figure 1 Regulation of endothelin-1 (ET-1) gene expression by verotoxin (VT). (a) ET-1 is transcribed from its highly inducible promoter, which produces a short-lived mRNA. (b) VT stabilizes ET-1 mRNA, resulting in increased steady-state mRNA levels. Kidney International  , S17-S19DOI: ( /ki ) Copyright © 2009 International Society of Nephrology Terms and Conditions


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