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Incidence of sperm aneuploidy in relation to semen characteristics and assisted reproductive outcome
Liliana T Colombero, M.D., June J Hariprashad, B.A., Ming C Tsai, M.D., Zev Rosenwaks, M.D., Gianpiero D Palermo, M.D. Fertility and Sterility Volume 72, Issue 1, Pages (July 1999) DOI: /S (99)
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Figure 1 Fluorescence in situ hybridization of human spermatozoa using probes for chromosomes 18 (green), X (yellow), and Y (red). The sperm chromatin is stained with 4′,6-diamino-2-phenylindole and appears blue. Normal haploid sperm nuclei are seen that exhibit one signal for chromosome 18 and one for chromosome X or Y. Fertility and Sterility , 90-96DOI: ( /S (99) )
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Figure 2 Fluorescence in situ hybridization of human spermatozoa using probes for chromosomes 21 (red), X (yellow), and Y (green). The sperm chromatin is stained with 4′,6-diamino-2-phenylindole and appears blue. Two normal haploid sperm nuclei are seen that exhibit one signal for chromosome 21 and one for chromosome X or Y. Fertility and Sterility , 90-96DOI: ( /S (99) )
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Figure 3 Examples of spermatozoa that carry chromosomal abnormalities. (A), A sperm head carrying a sex chromosome disomy (XX,21). (B), A sperm nucleus displaying an autosomal disomy (Y,2121). (C), A spermatozoon considered diploid (XX,1818). Fertility and Sterility , 90-96DOI: ( /S (99) )
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