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Volume 87, Issue 6, Pages (June 2015)

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1 Volume 87, Issue 6, Pages 1209-1215 (June 2015)
Incidence and risk factors for new-onset atrial fibrillation among patients with end-stage renal disease undergoing renal replacement therapy  Jo-Nan Liao, Tze-Fan Chao, Chia-Jen Liu, Kang-Ling Wang, Su-Jung Chen, Yenn-Jiang Lin, Shih-Lin Chang, Li-Wei Lo, Yu-Feng Hu, Ta-Chuan Tuan, Fa-Po Chung, Tzeng-Ji Chen, Shih-Ann Chen  Kidney International  Volume 87, Issue 6, Pages (June 2015) DOI: /ki Copyright © 2015 International Society of Nephrology Terms and Conditions

2 Figure 1 Cumulative event rate of new-onset atrial fibrillation (AF) in end-stage renal disease (ESRD), chronic kidney disease (CKD), and control patients. Log-rank test demonstrated a significantly different risk of new-onset AF among the three groups. As the cumulative incidence curve demonstrates, the ESRD group had a higher incidence rate than the CKD and control group. Kidney International  , DOI: ( /ki ) Copyright © 2015 International Society of Nephrology Terms and Conditions

3 Figure 2 Incidence and cumulative event rate of new-onset atrial fibrillation (AF) in end-stage renal disease (ESRD) patients with multiple risk factors. (a) The incidence of AF continuously increased in patients with multiple risk factors. (b) Patients were stratified into seven groups based on the number of risk factors they had. The cumulative incidence curve with log-rank test showed that patients with more risk factors had a higher rate of new-onset AF. *Number of new-onset AF per 1000 person-years of follow-up. Kidney International  , DOI: ( /ki ) Copyright © 2015 International Society of Nephrology Terms and Conditions

4 Figure 3 Flowchart of study enrollment. From 1996 to 2011, a total of 134,901 end-stage renal disease (ESRD) patients without a history of atrial fibrillation (AF) were identified from the National Health Insurance Research Database (NHIRD). For each ESRD patient, one age- and gender-matched subject with chronic kidney disease (CKD) and one similarly matched patient without CKD were selected from the NHIRD on the same date that the ESRD patient was enrolled. Kidney International  , DOI: ( /ki ) Copyright © 2015 International Society of Nephrology Terms and Conditions


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