1. The Role of the Kidney in Glucose Control

2. Hyperglycemia in Type 2 Diabetes

3. Sodium Glucose Cotransporters

4. Location of Sodium Glucose Cotransporters in the Kidney

5. SGLT2 Inhibitors

6. Rationale for SGLT2 Inhibitor Therapy*

7. Dapagliflozin* Added to Metformin

8. Dapagliflozin* – Sustained Effects on HbA1c and Body Weight

9. Additional Benefits of SGLT2 Inhibition*

10. Limitations of SGLT2 Inhibitors*

11. Limitations of SGLT2 Inhibitors* (cont)

12. Conclusions

13. Abbreviations

14. Abbreviations (cont)

15. Abbreviations (cont)

16. References

17. References (cont)

18. References (cont)

19. References (cont)

20. References (cont)

21. References (cont)

22. References (cont)

23. References (cont)

24. References (cont)