1. Opportunity Knocks… (Should I Answer?)
Kimberly E. Vanover, Ph.D.
Executive Director, Clinical Development
ASPET/APS Joint Mentoring Symposium
April 21, 2009
K. Vanover - Pathways to Leadership

2. Opportunities Arise from Transitions
From academia to industry
From big pharma to biotech
From bench scientist to management
From drug discovery to clinical development
From office commute to home office
April 21, 2009
K. Vanover - Pathways to Leadership

3. K. Vanover - Pathways to Leadership
Academia to Industry
Skill Sets
Grant writing
Manuscripts
Report writing
Press releases
Financial Pressures
Grants
Contracts
Investors
Partnerships
Outlook
Collaboration vs Competition
Timeframe IP
IP, intellectual property
April 21, 2009
K. Vanover - Pathways to Leadership

4. Big Pharma to Biotech Big Pharma Biotech Specialization More money,
Long timelines
Risk of therapeutic area switch
Biotech
Many hats
Hurry before the money runs out
Risk of all eggs in one basket
April 21, 2009
K. Vanover - Pathways to Leadership

5. Bench to Management Independence Conducting Own Experiments
Analyzing Own Data
More Physical Work
Taking on Direct Reports
Influencing Broader Scope
Dealing with More People Problems
Senior Management
Influencing Large Strategic Decisions
Increased Impact
Increased Pressure
April 21, 2009
K. Vanover - Pathways to Leadership

6. K. Vanover - Pathways to Leadership
Discovery to Clinical
Chemistry/CMC
New Molecular Entity
In Vitro
In Vivo
ADME/ DMPK
Pre-
Clinical
Phase I
Phase II
Phase III
New Drug Application
Toxicology
GLP
GMP
GCP
Regulatory
Affairs
product Profile
Target
CROs
ADME/DMPK, ; GCP, ; GLP, ; GMP,
Data Management
& Biostatistics
Documentation
Safety
Formulations
April 21, 2009
K. Vanover - Pathways to Leadership

7. Office Commute to Home Office
Team Support
Feel Connected
“In the Know”
Office Commute
Self-Motivation
Fewer Distractions
More Flexibility
Home Office
April 21, 2009
K. Vanover - Pathways to Leadership

8. K. Vanover - Pathways to Leadership
Transitions Allow for
More
Opportunity
Learning broader skills
Increasing flexibility & creativity
Taking more responsibility
April 21, 2009
K. Vanover - Pathways to Leadership

9. K. Vanover - Pathways to Leadership
Opportunity dances with those already on the dance floor. H. Jackson Brown, Jr. (author)
April 21, 2009
K. Vanover - Pathways to Leadership

10. Opportunity is Taken, Not Given
Don’t wait for someone to hand opportunity on a silver platter
Do take advantage of open doors
Don’t say, “that’s not my job”
Do look for what needs to be done and do it
Set your goal and start working towards it
Ask for what you want and ask for help
April 21, 2009
K. Vanover - Pathways to Leadership

11. Opportunity Knocks… Should I Answer?
Self
Career
Family
Make Compromises
Strike a Balance
April 21, 2009
K. Vanover - Pathways to Leadership

12. K. Vanover - Pathways to Leadership
Opportunity is missed by most people because it is dressed in overalls and looks like work. Thomas A. Edison (inventor, 1847 – 1931)
April 21, 2009
K. Vanover - Pathways to Leadership