Figure 20.1 Synthesis of PRPP.

Figure 20.1 Synthesis of PRPP.
Textbook of Biochemistry with Clinical Correlations, 7e edited by Thomas M. Devlin © 2011 John Wiley & Sons, Inc.

Figure 20.2 De novo synthesis of purine ribonucleotides.

Figure 20.3 Structure of N10-formyl H4folate.

Figure 20.4 Sources of carbon and nitrogen atoms in the purine ring.

Figure 20.5 Formation of AMP and GMP from IMP branch point.

Figure 20.6 Effects of allosteric modulators on molecular forms of glutamine PRPP amidotransferase.

Figure Glutamine PRPP amidotransferase activity as a function of glutamine or PRPP concentrations. Textbook of Biochemistry with Clinical Correlations, 7e edited by Thomas M. Devlin © 2011 John Wiley & Sons, Inc.

Figure 20.8 Regulation of purine nucleotide synthesis.

Figure 20.9 Salvage of purine nucleobases via phosphoribosyl transferases.

Figure 20.10 Interconversions of purine nucleotides.

Figure 20.11 Synthesis of tetrahydrobiopterin from GTP.

Figure 20.12 Degradation of purine nucleotides.

Figure 20.13 Reactions catalyzed by xanthine oxidoreductase (XOR).

Figure 20.14 De novo synthesis of pyrimidine nucleotides.

Figure 20.15 Formation of UTP from UMP.

Figure 20.16 Formation of cytidine 5’-triphosphate from uridine 5’-triphosphate CTP from UTP.

Figure 20.17 Regulation of CTP synthetase.

Figure 20.18 Sources of carbon and nitrogen atoms in pyrimidines.

Figure 20.19 Regulation of pyrimidine nucleotide synthesis.

Figure 20.20 De novo synthesis of 2’-deoxyribonucleotides from ribonucleotides.

Figure 20.21 Role of ribonucleotide reductase in DNA synthesis.

Figure 20.22 Structure of N5,N10-methylene H4folate.

Figure 20.23 Synthesis of 2’-deoxythymidine monophosphate.

Figure 20.24 Regulation of dCMP deaminase.

Figure Interconversions of pyrimidine nucleotides with emphasis on deoxyribonucleotide metabolism. Textbook of Biochemistry with Clinical Correlations, 7e edited by Thomas M. Devlin © 2011 John Wiley & Sons, Inc.

Figure 20.26 Pathways for degradation of pyrimidine nucleotides.

Figure 20.27 Degradation of uracil and thymine to end products.

Figure 20.28 Pathway for nicotinamide adenine nucleotide synthesis.

Figure 20.29 Synthesis of flavin of adenine dinucleotide.

Figure 20.30 Synthesis of coenzyme A.

Figure Structures of antimetabolites: 6-mercaptopurine, 5-fluorouracil, and cytosine arabinoside. Textbook of Biochemistry with Clinical Correlations, 7e edited by Thomas M. Devlin © 2011 John Wiley & Sons, Inc.

Figure 20.32 Comparison of the structures of folic acid and methotrexate.

Figure 20.33 Sites of inhibition of methotrexate.

Figure 20.34 Relationship between H4folate, de novo purine nucleotide synthesis, and dTMP synthesis.

Figure 20.35 Structures of hydroxyurea and tiazofurin.

Figure 20.36 Structures of the antiviral agents, acyclovir and AZT.

Figure 20.1 Synthesis of PRPP.

Similar presentations

Presentation on theme: "Figure 20.1 Synthesis of PRPP."— Presentation transcript:

Similar presentations

About project

Feedback

Log in

Auth with social network:

Figure 20.1 Synthesis of PRPP.

Similar presentations

Presentation on theme: "Figure 20.1 Synthesis of PRPP."— Presentation transcript:

Similar presentations

About project

Feedback