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Multimodal Signal Integration for Feeding Control

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Presentation on theme: "Multimodal Signal Integration for Feeding Control"— Presentation transcript:

1 Multimodal Signal Integration for Feeding Control
Marcus L. Basiri, Garret D. Stuber  Cell  Volume 165, Issue 3, Pages (April 2016) DOI: /j.cell Copyright © 2016 Elsevier Inc. Terms and Conditions

2 Figure 1 Ingestion Neurons (IN1) Reside in the Subesophageal Zone and Integrate Pharyngeal Gustatory Input with Hunger State to Modify Ingestion (A) Frontal view illustration of a Drosophila head during sucrose consumption, with brain (purple) and pertinent circuitry (green) overlaid. Region enclosed by line magnified in (B). (B) IN1 neurons reside in the subesophageal zone (SEZ) and receive synaptic input from sugar-sensitive gustatory neurons in the pharynx. IN1 neurons increase their activity in response to sucrose ingestion and display greater activity to higher sucrose concentrations. IN1 activity is greater in fasted flies and decreases over the course of ingestion as flies become satiated. Cell  , DOI: ( /j.cell ) Copyright © 2016 Elsevier Inc. Terms and Conditions

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