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Sinus bradycardia and chronotropic incompetence associated with single-agent itraconazole antifungal therapy: A case report  Julian Tokarev, BS, David.

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Presentation on theme: "Sinus bradycardia and chronotropic incompetence associated with single-agent itraconazole antifungal therapy: A case report  Julian Tokarev, BS, David."— Presentation transcript:

1 Sinus bradycardia and chronotropic incompetence associated with single-agent itraconazole antifungal therapy: A case report  Julian Tokarev, BS, David G. Benditt, MD, FHRS  HeartRhythm Case Reports  Volume 1, Issue 1, Pages 6-9 (January 2015) DOI: /j.hrcr Copyright © 2015 Heart Rhythm Society Terms and Conditions

2 Figure 1 Twelve-lead ECG obtained when the patient presented with complaints of fatigue and exertional limitation. The tracing reveals sinus rhythm at 44 bpm. A leftward axis is present and is new since his only ECG recorded 4 years earlier (see Figure 2). QT/QTc is prolonged (496/424 ms). HeartRhythm Case Reports 2015 1, 6-9DOI: ( /j.hrcr ) Copyright © 2015 Heart Rhythm Society Terms and Conditions

3 Figure 2 Twelve-lead ECG obtained 4 years before that shown in Figure 1 as part of a routine physical examination. This is the patient’s only prior ECG. At the time he was taking no cardioactive drugs. The tracing is normal, showing sinus rhythm with sinus arrhythmia and a heart rate averaging 65 bpm. QT/QTc is normal (386/404 ms). HeartRhythm Case Reports 2015 1, 6-9DOI: ( /j.hrcr ) Copyright © 2015 Heart Rhythm Society Terms and Conditions

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