1. Bellwork: 9/21 Put your phone up 
Week 9/17-9/21
Briefly summarize Madelyn’s story in 1-2 sentences

2. Today:
Finish Anorexia Packet

3. Materials
Anorexia Packet

4. Homework
None 

5. What happens to our bodies when we intake TOO many macromolecules?

6. What happens to our bodies when we intake TOO few macromolecules?

7. Unit II: Biochemistry

8. Part V: Enzymes

9. Intro Question
Someone says to you “you can eat as much as you want and never gain weight; you must have a high metabolism”. What do you think that statement means biochemically?

10. Chemical Reaction
A process that changes one set of chemicals into another
This change comes from breaking and/or forming new chemical bonds

11. Enzymes Types of proteins Speed up chemical reactions
Shapes & function have to match for them to be able to work
Speed up chemical reactions
A million times faster or more

12. Enzymes Enzymes make reactions go faster OR slower
To adjust metabolism
Have names ending in “-ase”
Ex. Lactase(enzyme) breaks down Lactose (Sugar)

13. Think-Pair-Share
What happens in the Catalytic Converter in a car? Why is a Catalytic Converter a good name?

15. How Enzymes Work Each enzyme has a unique shape
Works on a specific chemical
Substrate = chemical the enzyme works on
Each enzyme has an active site
VERY SPECIFIC
A slot or pocket that fits substrate perfectly

16. Enzyme

17. Active Site
Shape of Active Site
Complementary to shape of Substrate

18. Lock and Key Model The grooves and prongs of the key
Must be complementary to grooves and prongs of the lock
Like the Active Site and the Substrate
Must be complementary

19. Environmental Effect
Extreme environments can affect enzyme shape & binding of the Substrate
2 key environmental factors
High Temperature
pH too acidic or too basic
These environments cause the enzyme to denature (break down)

20. Environmental Effect Example: Digestive enzymes break down food
Enzymes build starch out of sugar
Organisms need 1000s of enzymes
Without enzymes, life would not survive